Successful Treatment of Disseminated Fusariosis with the Combination of Voriconazole and Liposomal Amphotericin B
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منابع مشابه
Resolution of disseminated fusariosis in a child with acute leukemia treated with combined antifungal therapy: a case report
BACKGROUND Fusarium spp. is being isolated with increasing frequency as a pathogen in oncohematologic patients. Caspofungin and amphotericin B have been reported to have synergistic activity against Fusarium spp. CASE PRESENTATION We herein report a case of disseminated fusariosis diagnosed by chest CT scan and positive blood cultures to Fusarium spp. Because the patient's clinical condition ...
متن کاملSuccessful outcome of disseminated Fusarium infection with skin localization treated with voriconazole and amphotericin B-lipid complex in a patient with acute leukemia.
A disseminated Fusarium oxysporum infection with skin localization was diagnosed in a woman with a relapse of B-acute leukemia during induction chemotherapy. The infection was refractory to amphotericin B-lipid complex alone but responded successfully when voriconazole was added.
متن کاملDisseminated fusariosis caused by Fusarium verticillioides in an acute lymphoblastic leukemia patient after allogeneic hematopoietic stem cell transplantation.
Fusarium species are saprophytic molds which cause disseminated or localized infections in humans. Disseminated Fusarium infection can cause significant morbidity and mortality in immunocompromised patients. We present a case of disseminated fusariosis caused by Fusarium verticillioides in a patient with acute lymphoblastic leukemia and successfully treated using both liposomal amphotericin B a...
متن کاملپروتکل استفاده از داروهای ضد قارچی در درمان عفونت های قارچی تهاجمی
Recently, despite the application of surgery and antifungal therapy, mortality rate of invasive fungal infections due to opportunistic fungi such as Candida and Aspergillus species has dramatically increased specially in immunocompromised host. The status of the immune system plays a key role in controlling the disease, yet antifungal therapy is of great benefit in saving involved patients. Tod...
متن کاملCombined therapy in treatment of murine infection by Fusarium solani.
OBJECTIVES We evaluated the efficacy of voriconazole, amphotericin B and micafungin alone and combined in a murine model of disseminated infection by Fusarium solani. METHODS Immunosuppressed mice were treated with voriconazole at 60 mg/kg/day, amphotericin B at 3 mg/kg/day, micafungin at 10 mg/kg/day or combinations of these antifungal drugs. For survival studies, treatment began 1 day after...
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